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1

The VPAC2 Receptor Is Essential for Circadian Function in the Mouse Suprachiasmatic Nuclei

Anthony J. Harmar, Hugh M. Marston, Sanbing Shen, Christopher Spratt, Katrine M. West, W.John Sheward, Christine F. Morrison, Julia R. Dorin, Hugh D. Piggins, Jean-Claude Reubi, John S. Kelly, Elizabe

Journal:

Year:

2002

Language:

english

File:

PDF, 620 KB

english, 2002

2

Functional classification of ATM variants in Ataxia‐Telangiectasia patients

Fievet, Alice, Bellanger, Dorine, Rieunier, Guillaume, Dubois d'Enghien, Catherine, Sophie, Julia, Calvas, Patrick, Carriere, Jean‐Paul, Anheim, Mathieu, Castrioto, Anna, Flabeau, Olivier, Degos, Bert

Journal:

Year:

2019

File:

PDF, 908 KB

2019

3

Structure–activity relationships in β-defensin peptides

Karen Taylor, Perdita E. Barran, Julia R. Dorin

Journal:

Year:

2008

Language:

english

File:

PDF, 188 KB

english, 2008

4

Synthesis of Cyclic Peptides through an Intramolecular Amide Bond Rearrangement

Dr. Derek Macmillan, Dr. Martin De Cecco, Dr. Natalie L. Reynolds, Dr. Luiz F. A. Santos, Dr. Perdita E. Barran, Dr. Julia R. Dorin

Journal:

Year:

2011

Language:

english

File:

PDF, 761 KB

english, 2011

5

Human β-defensin 3 has immunosuppressive activity in vitro and in vivo

Fiona Semple, Sheila Webb, Hsin-Ni Li, Hetal B. Patel, Mauro Perretti, Ian J. Jackson, Mohini Gray, Donald J. Davidson, Julia R. Dorin

Journal:

European Journal of Immunology

Year:

2010

Language:

english

File:

PDF, 227 KB

english, 2010

6

Human β-defensin 3 affects the activity of pro-inflammatory pathways associated with MyD88 and TRIF

Fiona Semple, Heather MacPherson, Sheila Webb, Sarah L. Cox, Lucy J. Mallin, Christine Tyrrell, Graeme R. Grimes, Colin A. Semple, Matthew A. Nix, Glenn L. Millhauser, Julia R. Dorin

Journal:

European Journal of Immunology

Year:

2011

Language:

english

File:

PDF, 314 KB

english, 2011

7

Is it biologically relevant to measure the structures of small peptides in the gas-phase?

Perdita E. Barran, Nick C. Polfer, Dominic J. Campopiano, David J. Clarke, Patrick R.R. Langridge-Smith, Ross J. Langley, John R.W. Govan, Alison Maxwell, Julia R. Dorin, Robert P. Millar, Michael T.

Journal:

International Journal of Mass Spectrometry

Year:

2005

Language:

english

File:

PDF, 446 KB

english, 2005

8

Instability of the insertional mutation inCftrTgH(neoim)Hgucystic fibrosis mouse model

Nikoletta Charizopoulou, Silke Jansen, Martina Dorsch, Frauke Stanke, Julia R Dorin, Hans-Jürgen Hedrich, Burkhard Tümmler

Journal:

Year:

2004

Language:

english

File:

PDF, 1.39 MB

english, 2004

9

Successful targeting of the mouse cystic fibrosis transmembrane conductance regulator gene in embryonal stem cells

Julia R. Dorin, Paul Dickinson, Elizabeth Emslie, Alan R. Clarke, Lorraine Dobbie, Martin L. Hooper, Stephanie Halford, Brandon J. Wainwright, David J. Porteous

Journal:

Transgenic Research

Year:

1992

Language:

english

File:

PDF, 1.06 MB

english, 1992

10

Identification and characterization of a novel murine beta-defensin-related gene

Gillian M. Morrison, Mark Rolfe, Fiona M. Kilanowski, Sally H. Cross, Julia R. Dorin

Journal:

Mammalian Genome

Year:

2002

Language:

english

File:

PDF, 233 KB

english, 2002

11

Submucosal gland distribution in the mouse has a genetic determination localized on Chromosome 9

Brendan A. Innes, Julia R. Dorin

Journal:

Mammalian Genome

Year:

2001

Language:

english

File:

PDF, 352 KB

english, 2001

12

Mouse beta defensin-1 is a functional homolog of human beta defensin-1

Gillian M. Morrison, Donald J. Davidson, Fiona M. Kilanowski, Duncan W. Borthwick, Ken Crook, Alison I. Maxwell, John R.W. Govan, Julia R. Dorin

Journal:

Mammalian Genome

Year:

1998

Language:

english

File:

PDF, 375 KB

english, 1998

13

The changing of the guard: Molecular diversity and rapid evolution of β-defensins

Colin A. Semple, Phillipe Gautier, Karen Taylor, Julia R. Dorin

Journal:

Molecular Diversity

Year:

2006

Language:

english

File:

PDF, 338 KB

english, 2006

14

Characterisation of DEFB107 by mass spectrometry: Lessons from an anti-antimicrobial defensin

Bryan J. McCullough, Hayden Eastwood, Dave J. Clark, Nick C. Polfer, Dominic J. Campopiano, Julia A Dorin, Alison Maxwell, Ross J. Langley, John R.W. Govan, Summer L. Bernstein, Michael T. Bowers, Per

Journal:

International Journal of Mass Spectrometry

Year:

2006

Language:

english

File:

PDF, 308 KB

english, 2006

15

A clue to the basic defect in cystic fibrosis from cloning the CF antigen gene

Dorin, Julia R., Novak, Michal, Hill, Robert E., Brock, David J. H., Secher, David S., van Heyningen, Veronica

Journal:

Year:

1987

File:

PDF, 583 KB

1987

16

Cystic fibrosis in the mouse by targeted insertional mutagenesis

Dorin, Julia R., Dickinson, Paul, Alton, Eric W. F. W., Smith, Stephen N., Geddes, Duncan M., Stevenson, Barbara J., Kimber, Wendy L., Fleming, Stewart, Clarke, Alan R., Hooper, Martin L.

Journal:

Year:

1992

File:

PDF, 832 KB

1992

17

10.1038/37987

Cooke, Howard J., Ruggiu, Matteo, Speed, Robert, Taggart, Mary, McKay, Stewart J., Kilanowski, Fiona, Saunders, Philippa, Dorin, Julia

Journal:

Year:

1997

Language:

english

File:

PDF, 810 KB

english, 1997

18

Lung disease in the cystic fibrosis mouse exposed to bacterial pathogens

Davidson, Donald J., Dorin, Julia R., McLachlan, Gerard, Ranaldi, Vincent, Lamb, David, Doherty, Catherine, Govan, John, Porteous, David J.

Journal:

Nature Genetics

Year:

1995

File:

PDF, 1.03 MB

1995

19

Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis

Caplen, Natasha J., Alton, Eric W.F.W., Mddleton, Peter G., Dorin, Julia R., Stevenson, Barbara J., Gao, Xiang, Durham, Stephen R., Jeffery, Peter K., Hodson, Margaret E., Coutelle, Charles

Journal:

Nature Medicine

Year:

1995

File:

PDF, 923 KB

1995

20

Enhancing the efficiency of introducing precise mutations into the mouse genome by hit and run gene targeting

Paul Dickinson, Wendy L. Kimber, Fiona M. Kilanowski, Sheila Webb, Barbara J. Stevenson, David J. Porteous, Julia R. Dorin

Journal:

Transgenic Research

Year:

2000

Language:

english

File:

PDF, 133 KB

english, 2000

21

ß-Defensins: Multifunctional Modulators of Infection, Inflammation and More?

Semple, Fiona, Dorin, Julia R.

Journal:

Journal of Innate Immunity

Year:

2012

Language:

english

File:

PDF, 415 KB

english, 2012

22

SV40-mediated tumor selection and chromosome transfer to enrich for cystic fibrosis region

David J. Porteous, Julia R. Dorin, Maureen M. Wilkinson, Judy M. Fletcher, Elisabeth Emslie, Veronica van Heyningen

Journal:

Somatic Cell and Molecular Genetics

Year:

1990

Language:

english

File:

PDF, 886 KB

english, 1990

23

Cystic fibrosis — the way forward from the gene

Julia R. Dorin, David J. Porteous

Journal:

Trends in Biotechnology

Year:

1991

Language:

english

File:

PDF, 749 KB

english, 1991

24

Cystic fibrosis — the way forward from the gene

Julia R. Dorin, David J. Porteous

Journal:

Trends in Biotechnology

Year:

1991

Language:

english

File:

PDF, 614 KB

english, 1991

25

How relevant are mouse models for human diseases to somatic gene therapy?

David J. Porteous, Julia R. Dorin

Journal:

Trends in Biotechnology

Year:

1993

Language:

english

File:

PDF, 1.00 MB

english, 1993

26

Genetic engineering: J.G. Williams, A. Ceccarelli and N. Spur Bios scientific publishers, 1993. £14.00/$28.00 pbk (x + 132 pages) isbn 1 872748 75 9

Journal:

Trends in Genetics

Year:

1993

Language:

english

File:

PDF, 116 KB

english, 1993

27

Expansion of circulating NKG2D+ effector memory T-cells and expression of NKG2D-ligand MIC in granulomaous lesions in Wegener's granulomatosis

Dorin Capraru, Antje Müller, Elena Csernok, Wolfgang L. Gross, Konstanze Holl-Ulrich, John Northfield, Paul Klenerman, Karen Herlyn, Julia Holle, Stefan Gottschlich, Jan Voswinkel, Thomas Spies, Ursul

Journal:

Clinical Immunology

Year:

2008

Language:

english

File:

PDF, 1.09 MB

english, 2008

28

Rare corneal clones in mice suggest an age-related decrease of stem cell activity and support the limbal epithelial stem cell hypothesis

Panagiotis Douvaras, Sheila Webb, Duncan A. Whitaker, Natalie Dorà, Robert E. Hill, Julia R. Dorin, John D. West

Journal:

Stem Cell Research

Year:

2012

Language:

english

File:

PDF, 1.15 MB

english, 2012

29

A curate's egg – good in parts

Journal:

Trends in Genetics

Year:

2001

Language:

english

File:

PDF, 22 KB

english, 2001

30

The complexity of selection at the major primate β-defensin locus

Colin AM Semple, Alison Maxwell, Philippe Gautier, Fiona M Kilanowski, Hayden Eastwood, Perdita E Barran, Julia R Dorin

Journal:

BMC Evolutionary Biology

Year:

2005

Language:

english

File:

PDF, 560 KB

english, 2005

31

Isoleucine/leucine2 is essential for chemoattractant activity of β-defensin Defb14 through chemokine receptor 6

Christine Tyrrell, Martin De Cecco, Natalie L. Reynolds, Fiona Kilanowski, Dominic Campopiano, Perdita Barran, Derek Macmillan, Julia R. Dorin

Journal:

Molecular Immunology

Year:

2010

Language:

english

File:

PDF, 405 KB

english, 2010

32

A novel mouse beta defensin, Defb2, which is upregulated in the airways by lipopolysaccharide

Gillian M Morrison, Donald J Davidson, Julia R Dorin

Journal:

Year:

1999

Language:

english

File:

PDF, 273 KB

english, 1999

33

Modelling cystic fibrosis in the mouse

Paul Dickinson, Julia R. Dorin, David J. Porteous

Journal:

Molecular Medicine Today

Year:

1995

Language:

english

File:

PDF, 7.52 MB

english, 1995

34

Peptide thioester synthesis through N→S acyl-transfer: application to the synthesis of a β-defensin

Kang, Jaskiranjit, Reynolds, Natalie L., Tyrrell, Christine, Dorin, Julia R., Macmillan, Derek

Journal:

Organic & Biomolecular Chemistry

Year:

2009

Language:

english

File:

PDF, 246 KB

english, 2009

35

Murine epithelial cells: isolation and culture

Donald J. Davidson, Michael A. Gray, Fiona M. Kilanowski, Robert Tarran, Scott H. Randell, David N. Sheppard, Barry E. Argent, Julia R. Dorin

Journal:

Journal of Cystic Fibrosis

Year:

2004

Language:

english

File:

PDF, 88 KB

english, 2004

36

15-P038 Stra6.2: A novel member of the STRA6 gene family

Niki Wyatt, Chris Ponting, Julia Dorin, David Fitzpatrick, Robert Hill

Journal:

Mechanisms of Development

Year:

2009

Language:

english

File:

PDF, 38 KB

english, 2009

37

Following damage, the majority of bone marrow-derived airway cells express an epithelial marker

Heather MacPherson, Pamela A Keir, Carol J Edwards, Sheila Webb, Julia R Dorin

Journal:

Respiratory Research

Year:

2006

Language:

english

File:

PDF, 3.22 MB

english, 2006

38

Development of an Ion Mobility Quadrupole Time of Flight Mass Spectrometer

McCullough, Bryan J., Kalapothakis, Jason, Eastwood, Hayden, Kemper, Paul, MacMillan, Derek, Taylor, Karen, Dorin, Julia, Barran, Perdita E.

Journal:

Analytical Chemistry

Year:

2008

Language:

english

File:

PDF, 733 KB

english, 2008

39

Duplication and selection in the evolution of primate β-defensin genes

Colin AM Semple, Mark Rolfe, Julia R Dorin

Journal:

Year:

2003

Language:

english

File:

PDF, 303 KB

english, 2003

40

355 MOLECULAR MECHANISMS OF DEFB1: A NEW TUMOR SUPPRESSOR GENE IN RENAL AND PROSTATE CANCERS

Sun, Carrie, Arnold, Rebecca, Marshall, Fray, Dorin, Julia, Petros, John

Journal:

The Journal of Urology

Year:

2010

Language:

english

File:

PDF, 42 KB

english, 2010

41

The Mouse Bagpipe Gene Controls Development of Axial Skeleton, Skull, and Spleen

Laura A. Lettice, Lorna A. Purdie, Geoffrey J. Carlson, Fiona Kilanowski, Julia Dorin and Robert E. Hill

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 2.06 MB

english, 1999

42

Conformational Preferences of Linear β-Defensins Are Revealed by Ion Mobility-Mass Spectrometry

Cecco, Martin De, Seo, Emily S., Clarke, David J., McCullough, Bryan J., Taylor, Karen, Macmillan, Derek, Dorin, Julia R., Campopiano, Dominic J., Barran, Perdita E.

Journal:

Journal of Physical Chemistry B

Year:

2010

Language:

english

File:

PDF, 234 KB

english, 2010

43

Molecular Medical Microbiology || Mammalian Antimicrobial Peptides; Defensins and Cathelicidins

Dorin, Julia R.

Year:

2015

Language:

english

File:

PDF, 1.77 MB

english, 2015

44

Binding a heparin derived disaccharide to defensin inspired peptides: insights to antimicrobial inhibition from gas-phase measurements

McCullough, Bryan J., Kalapothakis, Jason M., Chin, Wutharath, Taylor, Karen, Clarke, David J., Eastwood, Hayden, Campopiano, Dominic, MacMillan, Derek, Dorin, Julia, Barran, Perdita E.

Journal:

Physical Chemistry Chemical Physics

Year:

2010

Language:

english

File:

PDF, 1.32 MB

english, 2010

45

Evidence for Stem-Cell Niches in the Tracheal Epithelium

Borthwick, Duncan W., Shahbazian, Mariam, Todd Krantz, Q., Dorin, Julia R., Randell, Scott H.

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2001

Language:

english

File:

PDF, 608 KB

english, 2001

46

mc1r Pathway Regulation of Zebrafish Melanosome Dispersion

Richardson, Jennifer, Lundegaard, Pia Rengtved, Reynolds, Natalie L., Dorin, Julia R., Porteous, David J., Jackson, Ian J., Patton, E. Elizabeth

Journal:

Year:

2008

Language:

english

File:

PDF, 10.33 MB

english, 2008

47

Gene therapy for cystic fibrosis—Where and When?

Porteous, David J., Dorin, Julia R.

Journal:

Human Molecular Genetics

Year:

1993

Language:

english

File:

PDF, 231 KB

english, 1993

48

The CF mouse: an important tool for studying cystic fibrosis

Davidson, Donald J., Dorin, Julia R.

Journal:

Expert Reviews in Molecular Medicine

Year:

2001

Language:

english

File:

PDF, 628 KB

english, 2001

49

Gene targeting for somatic cell manipulation: rapid analysis of reduced chromosome hybrids by Alu -PCR fingerprinting and chromosome painting

Dorin, Julia R., Emslie, Elizabeth, Hanratty, Diane, Farrall, Martin, Gosden, John, J.Porteous, David

Journal:

Human Molecular Genetics

Year:

1992

Language:

english

File:

PDF, 5.70 MB

english, 1992

50

High frequency gene targeting using insertional vectors

Dickinson, Paul, Kimber, Wendy L., Kilanowski, Fiona M., Stevenson, Barbara J., Porteous, David J., Dorin, Julia R.

Journal:

Human Molecular Genetics

Year:

1993

Language:

english

File:

PDF, 2.05 MB

english, 1993